CD300a antibody (PE)

Catalog No. ABIN4369567

Product Details anti-CD300a Antibody (PE)

Target: CD300a (CD300A)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD300a antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against native CD300A.

Specificity: This antibody reacts with CD300a, a 60 KDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25 % of circulating T cells and 15 % of circulating B cells.

Cross-Reactivity: Human

Immunogen: Native purified CD300A from human HPB acute lymphoid leukaemia cell line.

Clone: MEM-260

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-CD300a antibody (PE) (ABIN4369567)

Dimasi, Roessle, Moran, Candiano, Svergun, Biassoni: "Molecular analysis and solution structure from small-angle X-ray scattering of the human natural killer inhibitory receptor IRp60 (CD300a)." in: International journal of biological macromolecules, Vol. 40, Issue 3, pp. 193-200, (2007) (PubMed).

Alvarez, Tang, Coligan, Borrego: "The CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcgammaRIIa) mediated signaling." in: Molecular immunology, Vol. 45, Issue 1, pp. 253-8, (2007) (PubMed).

Bachelet, Munitz, Levi-Schaffer: "Abrogation of allergic reactions by a bispecific antibody fragment linking IgE to CD300a." in: The Journal of allergy and clinical immunology, Vol. 117, Issue 6, pp. 1314-20, (2006) (PubMed).

Target Details for CD300a

Target: CD300a (CD300A)

Alternative Name: CD300A / CMRF35H (CD300A Products)

Synonyms: CD300L-B1 antibody, CD300A antibody, clm8 antibody, B230315M08Rik antibody, Clm8 antibody, LMIR1 antibody, MAIR-I antibody, MAIR-Ia antibody, MMAC8 antibody, Pigr4 antibody, mcpir1 antibody, CLM-8 antibody, CMRF-35-H9 antibody, CMRF-35H antibody, CMRF35-H antibody, CMRF35-H9 antibody, CMRF35H antibody, CMRF35H9 antibody, IGSF12 antibody, IRC1 antibody, IRC1/IRC2 antibody, IRC2 antibody, IRp60 antibody, CD300 molecule like family member g antibody, CD300a molecule antibody, CMRF35-like molecule 8 antibody, CD300A molecule antibody, Cd300a molecule antibody, CD300LG antibody, CD300A antibody, LOC483289 antibody, clm8 antibody, Cd300a antibody

Gene ID: 11314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process