ORC6 antibody (C-Term)

Catalog No. ABIN452310

Product Details anti-ORC6 Antibody

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ORC6 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody recognizes ORC6.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence C-ENAASAQKATAE, from the C Terminus of the protein sequence (NP_055136.1) . Genename: ORC6L

Application Details

Application Notes: Western blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ORC6

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Alternative Name: ORC6 (ORC6 Products)

Synonyms: Orc6l antibody, CG1584 antibody, DmORC 6 antibody, DmORC6 antibody, Dmel\\CG1584 antibody, ORC antibody, ORC6 antibody, orc6 antibody, rDmORC antibody, ORC6L antibody, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 antibody, ATORC6 antibody, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 antibody, T2P11.3 antibody, T2P11_3 antibody, origin recognition complex protein 6 antibody, DDBDRAFT_0186183 antibody, DDBDRAFT_0233113 antibody, DDB_0186183 antibody, DDB_0233113 antibody, LOC100284755 antibody, orc6l antibody, 6720420I10Rik antibody, origin recognition complex, subunit 6 antibody, Origin recognition complex subunit 6 antibody, origin recognition complex subunit 6 antibody, origin recognition complex protein 6 antibody, origin recognition complex subunit Orc6 antibody, Orc6 antibody, ORC6 antibody, CpipJ_CPIJ005016 antibody, SJAG_01267 antibody, orcF antibody, LOC100284755 antibody, orc6 antibody

Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.Synonyms: ORC6L, Origin recognition complex subunit 6

Molecular Weight: 28.1kDa (NP_055136.1).

Gene ID: 23594

NCBI Accession: NP_055136

UniProt: Q9Y5N6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA