DISP1 antibody (C-Term)

Catalog No. ABIN452438

Product Details anti-DISP1 Antibody

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This DISP1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Specificity: This antibody reacts to Dispatched homolog 1.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography.

Immunogen: Peptide with sequence C-SELSGESLLIKTL, from the C Terminus of the protein sequence.

Application Details

Application Notes: Peptide ELISA: Detection limit: 1/32000. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for DISP1

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Alternative Name: DISP1 / DISPA (DISP1 Products)

Synonyms: DISP1 antibody, DISPA antibody, 1190008H24Rik antibody, DispA antibody, con antibody, zgc:111866 antibody, dispatched antibody, dispatched RND transporter family member 1 antibody, dispatched homolog 1 (Drosophila) antibody, CpipJ_CPIJ008642 antibody, DISP1 antibody, Disp1 antibody, disp1 antibody

Background: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. Dispatched is a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells.Synonyms: Protein dispatched homolog 1

Gene ID: 84976

NCBI Accession: NP_116279

UniProt: Q96F81

Pathways: Hedgehog Signaling