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FPR2 antibody (AA 181-192)
FPR2
Reactivity: Human
WB, EIA
Host: Mouse
Monoclonal
B4D9B10
unconjugated
Product Details anti-FPR2 Antibody
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Target
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FPR2
(Formyl Peptide Receptor 2 (FPR2))
Binding Specificity
All epitopes for FPR2 antibodies
AA 181-192
Reactivity
All reactivities for FPR2 antibodies
Human
Host
All hosts for FPR2 antibodies
Mouse
Clonality
All clonalities for FPR2 antibodies
Monoclonal
Conjugate
All conjugates for FPR2 antibodies
This FPR2 antibody is un-conjugated
Application
All applications for FPR2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This monoclonal antibody reacts with the above mentioned peptide in ELISA and reacts with the 38KDa FPRL1 on Western Blot.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Characteristics
Synonyms: N-formyl peptide receptor 2, FMLP-R-I, FPRH1, RFP, LXA4R, FMLP-related receptor I, Formylpeptide receptor-like 1, Lipoxin A4 receptor
Purification
Affinity Chromatography.
Immunogen
A short KLH conjugated peptide corresponding to the amino acid sequence 181-192(ASWGGTPEERLK) on Human FPRL1
Clone
B4D9B10
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
ELISA. Western Blot (1/1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Reconstitution
Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL
Buffer
0.01 M PBS, pH 7.2 without preservatives
Preservative
Without preservative
Storage
-20 °C
Storage Comment
Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Expiry Date
12 months
Target Details for FPR2
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Target
FPR2
(Formyl Peptide Receptor 2 (FPR2))
Alternative Name
FPR2 / FPRL1 (FPR2 Products )
Synonyms
ALXR antibody, FMLP-R-II antibody, FMLPX antibody, FPR2A antibody, FPRH1 antibody, FPRH2 antibody, FPRL1 antibody, HM63 antibody, LXA4R antibody, E330010I07Rik antibody, Fpr-rs2 antibody, Fprl1 antibody, ALX antibody, Fpr-rs1 antibody, Fpr-s1 antibody, LXA4-R antibody, Lxa4r antibody, FMLP-R-I antibody, FPR2 antibody, formyl peptide receptor 2 antibody, formyl peptide receptor 3 antibody, N-formyl peptide receptor 2 antibody, FPR2 antibody, Fpr2 antibody, Fpr3 antibody, LOC100444626 antibody
Background
FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.Synonyms: FMLP-R-I, FMLP-related receptor I, FPRH1, Formyl peptide receptor-like 1, LXA4R, Lipoxin A4 receptor, N-formyl peptide receptor 2, RFP
Gene ID
2358
UniProt
P25090
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