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TNK2 antibody (Middle Region)

TNK2 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN452710
  • Target See all TNK2 Antibodies
    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
    Binding Specificity
    • 22
    • 15
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 123
    • 51
    • 46
    • 3
    • 2
    • 2
    Human
    Host
    • 120
    • 3
    • 1
    Rabbit
    Clonality
    • 122
    • 1
    Polyclonal
    Conjugate
    • 50
    • 11
    • 11
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This TNK2 antibody is un-conjugated
    Application
    • 96
    • 69
    • 26
    • 26
    • 26
    • 20
    • 16
    • 12
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TNK2 / ACK1 at Center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide selected from the Center region of human ACK1
    Top Product
    Discover our top product TNK2 Primary Antibody
  • Application Notes
    ELISA: 1: 1,000. Western blot: 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
    Alternative Name
    TNK2 / ACK1 (TNK2 Products)
    Synonyms
    ACK antibody, ACK-1 antibody, ACK1 antibody, p21cdc42Hs antibody, AW552477 antibody, Ack antibody, Cdgip antibody, Pyk1 antibody, ack1 antibody, ackb antibody, tnk2 antibody, tnk2b antibody, wu:fj16g04 antibody, zgc:154019 antibody, tyrosine kinase non receptor 2 antibody, tyrosine kinase, non-receptor, 2 antibody, tyrosine kinase, non-receptor, 1 antibody, TNK2 antibody, Tnk2 antibody, tnk1 antibody
    Background
    ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1
    Molecular Weight
    114327 Da
    Gene ID
    10188
    NCBI Accession
    NP_001010938
    UniProt
    Q07912
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