Corin antibody (Middle Region)

Catalog No. ABIN452862

Product Details anti-Corin Antibody

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects CORIN at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CORIN

Application Details

Application Notes: Western blot: 1: 100 - 1: 500. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Alternative Name: CORIN (CORIN Products)

Synonyms: CORIN antibody, CG2105 antibody, Dmel\\CG2105 antibody, SP75 antibody, LOC559109 antibody, AV273130 antibody, Lrp4 antibody, ATC2 antibody, CRN antibody, PEE5 antibody, TMPRSS10 antibody, corin, serine peptidase antibody, CG2105 gene product from transcript CG2105-RC antibody, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) antibody, corin antibody, CORIN antibody, Corin antibody, LOC559109 antibody

Background: CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. This protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.Synonyms: ATC2, Atrial natriuretic peptide-converting enzyme, CRN, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, TMPRSS10, Transmembrane protease serine 10

Molecular Weight: 116565 Da

Gene ID: 10699

NCBI Accession: NP_006578

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones