FPGS antibody (Middle Region)

Catalog No. ABIN453030

Product Details anti-FPGS Antibody

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPGS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects FPGS at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human FPGS

Application Details

Application Notes: Western blot: 1: 100 - 1: 500. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for FPGS

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Alternative Name: FPGS (FPGS Products)

Synonyms: zgc:63807 antibody, wu:fk49h03 antibody, wu:fk51d09 antibody, FPGS antibody, fpgS antibody, SCC88.25c antibody, BA4689 antibody, AA408187 antibody, folylpolyglutamate synthase antibody, dihydrofolate synthase antibody, folylpolyglutamate synthase, mitochondrial antibody, folylpolyglutamyl synthetase antibody, fpgs antibody, fpgS antibody, FPGS antibody, SCO2614 antibody, fgs antibody, folC antibody, CpipJ_CPIJ008043 antibody, Fpgs antibody

Background: FPGS is the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives.Synonyms: Folylpoly-gamma-glutamate synthetase, Folylpolyglutamate synthase, Tetrahydrofolate synthase, Tetrahydrofolylpolyglutamate synthase

Molecular Weight: 64609 Da

Gene ID: 2356

NCBI Accession: NP_001018088

UniProt: Q05932