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Fucosidase, alpha-L- 1, Tissue (FUCA1) (Middle Region) antibody

Details for Product No. ABIN453036, Supplier: Log in to see
Antigen
  • 0610006A03Rik
  • 9530055J05Rik
  • Afuc
  • alpha-L-fucosidase 1
  • ATFUC1
  • F24D13.11
  • F24D13_11
  • Fuca
  • fuca
  • FUCA
  • fuca1
  • FUCA1
  • wu:fj17c05
Epitope
Middle Region
8
5
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Human
59
28
26
10
3
1
Host
Rabbit
63
14
1
Clonality
Polyclonal
Conjugate
Un-conjugated
7
4
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
55
35
13
11
9
6
4
4
3
3
3
3
3
3
Supplier
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Immunogen KLH conjugated synthetic peptide selected from the Center region of human FUCA1
Specificity This antibody detects FUCA1 at Center.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name alpha-L-Fucosidase 1 (FUCA1 Antibody Abstract)
Background FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.Synonyms: Alpha-L-fucosidase I, Alpha-L-fucoside fucohydrolase, FUCA1, Nbla10230, Tissue alpha-L-fucosidase
Molecular Weight 53689 Da
Gene ID 2517
NCBI Accession NP_000138
UniProt P04066
Application Notes Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.31 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Fucosidase, alpha-L- 1, Tissue (FUCA1) (Middle Region) antibody (ABIN453036) Western blot analysis of FUCA1 Antibody (Center) in HepG2 cell line lysates (35 µg/la...
Background publications Palmieri, Wilson, Iversen, Clyde, Calingaert, Moorman, Poole, Anderson, Anderson, Anton-Culver, Beesley, Hogdall, Brewster, Carney, Chen, Chenevix-Trench, Chang-Claude, Cunningham, Dicioccio, Doherty et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. ..." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008