KHSRP antibody (N-Term)

Catalog No. ABIN453148

Product Details anti-KHSRP Antibody

Target: KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHSRP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to KHSRP.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human KHSRP

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KHSRP

Target: KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))

Alternative Name: KHSRP (KHSRP Products)

Synonyms: FBP2 antibody, FUBP2 antibody, KSRP antibody, 6330409F21Rik antibody, Fbp2 antibody, Fubp2 antibody, Ksrp antibody, Marta1 antibody, KHSRP antibody, VgRBP71 antibody, fbp2 antibody, ksrp antibody, fubp2 antibody, fc94c12 antibody, wu:fb25b12 antibody, wu:fc10e10 antibody, wu:fc94c12 antibody, zgc:163038 antibody, khsrp-b antibody, KH-type splicing regulatory protein antibody, KH-type splicing regulatory protein L homeolog antibody, KH-type splicing regulatory protein S homeolog antibody, KHSRP antibody, Khsrp antibody, khsrp.L antibody, khsrp antibody, khsrp.S antibody

Background: KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). It is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) and activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.Synonyms: FUBP2, FUSE-binding protein 2, Far upstream element-binding protein 2, KH type-splicing regulatory protein, KHSRP, KSRP, p75

Gene ID: 8570

NCBI Accession: NP_003676

UniProt: Q92945