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RRM2 antibody (Ribonucleotide Reductase M2) (Middle Region)

Details for Product anti-RRM2 Antibody No. ABIN453352, Supplier: Log in to see
Antigen
  • RRM2
  • rrm2
  • rr2m
  • R2
  • RR2
  • RR2M
  • AA407299
  • cb111
  • chunp6884
  • r2
Epitope
Middle Region
6
6
4
4
4
3
3
2
2
1
1
1
Reactivity
Human
63
23
23
1
1
1
1
Host
Rabbit
47
14
2
Clonality
Polyclonal
Conjugate
This RRM2 antibody is un-conjugated
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
46
20
14
13
12
11
4
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide selected from the Center region of human RRM2
Specificity This antibody reacts to RRM2.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name RRM2 / RR2 (RRM2 Antibody Abstract)
Background RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.Synonyms: Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit
Gene ID 6241
NCBI Accession NP_001025
UniProt P31350
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-RRM2 antibody (Ribonucleotide Reductase M2) (Middle Region) (ABIN453352) Western blot analysis of RRM2 antibody (Center) in Jurkat cell line lysates (35ug/lan...
Background publications Liu, Xue, Yen: "Redox property of ribonucleotide reductase small subunit M2 and p53R2." in: Methods in molecular biology (Clifton, N.J.), Vol. 477, pp. 195-206, 2008 (PubMed).

Kolesar, Huang, Eickhoff et al.: "Evaluation of mRNA by Q-RTPCR and protein expression by AQUA of the M2 subunit of ribonucleotide reductase (RRM2) in human tumors." in: Cancer chemotherapy and pharmacology, Vol. 64, Issue 1, pp. 79-86, 2009 (PubMed).