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NOD1 antibody (C-Term)

NOD1 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN453551
  • Target See all NOD1 Antibodies
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    Binding Specificity
    • 11
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 42
    • 21
    • 14
    Human
    Host
    • 45
    • 3
    • 1
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOD1 antibody is un-conjugated
    Application
    • 40
    • 23
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes CARD4 / NOD1 (C-term).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography on Protein A.
    Immunogen
    KLH conjugated synthetic peptide selected from the C-terminal region of Human CARD4. Genename: NOD1
    Top Product
    Discover our top product NOD1 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    Alternative Name
    CARD4 / NOD1 (NOD1 Products)
    Synonyms
    CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, C230079P11 antibody, Card4 antibody, F830007N14Rik antibody, Nlrc1 antibody, RGD1562269 antibody, nucleotide binding oligomerization domain containing 1 antibody, nucleotide-binding oligomerization domain containing 1 antibody, NOD1 antibody, Nod1 antibody
    Background
    CARD4 is a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.Synonyms: Caspase recruitment domain-containing protein 4, Nucleotide-binding oligomerization domain-containing protein 1
    Molecular Weight
    107691 Da
    Gene ID
    10392
    NCBI Accession
    NP_006083
    UniProt
    Q9Y239
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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