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COQ3 antibody (Middle Region)

COQ3 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN453581
  • Target See all COQ3 Antibodies
    COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
    Binding Specificity
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 26
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 5
    Rabbit
    Clonality
    • 24
    • 2
    Polyclonal
    Conjugate
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    This COQ3 antibody is un-conjugated
    Application
    • 20
    • 14
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to COQ3.
    Purification
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide selected from the Center region of human COQ3
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    Discover our top product COQ3 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
    Alternative Name
    COQ3 (COQ3 Products)
    Synonyms
    4732433J24 antibody, C77934 antibody, DHHBMT antibody, DHHBMTASE antibody, UG0215E05 antibody, bA9819.1 antibody, ATCOQ3 antibody, EMB3002 antibody, F7F1.13 antibody, F7F1_13 antibody, coenzyme Q 3 antibody, embryo defective 3002 antibody, coenzyme Q3 methyltransferase antibody, coenzyme Q3, methyltransferase antibody, coenzyme Q 3 antibody, Coq3 antibody, COQ3 antibody
    Background
    Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. COQ3 is an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.Synonyms: 3, 4-dihydroxy-5-hexaprenylbenzoate methyltransferase, DHHB methyltransferase, DHHB-MTase, Dihydroxyhexaprenylbenzoate methyltransferase, mitochondrial Hexaprenyldihydroxybenzoate methyltransferase
    Gene ID
    51805
    NCBI Accession
    NP_059117
    UniProt
    Q9NZJ6
    Pathways
    Methionine Biosynthetic Process
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