KLRC1 antibody (C-Term)

Catalog No. ABIN453718

Product Details anti-KLRC1 Antibody

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to KLRC1 / CD159a.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the C-term region of human KLRC1.

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KLRC1

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Alternative Name: KLRC1 / CD159a (KLRC1 Products)

Synonyms: rNKG2A antibody, NKG2-A antibody, NKG2A antibody, KLRC1 antibody, CD159A antibody, NKG2 antibody, CD159a antibody, NKG2B antibody, killer cell lectin like receptor C1 antibody, NKG2-A/NKG2-B type II integral membrane protein-like antibody, killer cell lectin-like receptor subfamily C, member 3 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, Klrc1 antibody, KLRC1 antibody, NKG2A antibody, KLRC3 antibody

Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.Synonyms: CD159 antigen-like family member A, CD159a, KLRC1, NK cell receptor A, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, NKG2A

Gene ID: 3821

NCBI Accession: NP_002250

UniProt: P26715