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MARC2 antibody (Mitochondrial Amidoxime Reducing Component 2) (C-Term)

Details for Product anti-MARC2 Antibody No. ABIN453749, Supplier: Log in to see
Antigen
  • MOSC2
  • RP11-270A6.1
  • 2810484M10Rik
  • Mosc2
  • mARC1
  • Mg87
  • mARC2
Epitope
C-Term
32
15
1
1
1
Reactivity
Human
28
9
Host
Rabbit
37
Clonality
Polyclonal
Conjugate
This MARC2 antibody is un-conjugated
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
35
30
3
2
2
Supplier
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Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human MOSC2
Specificity This antibody reacts to MOSC2.
Purification Affinity chromatography on Protein A
Alternative Name MOSC2 (MARC2 Antibody Abstract)
Background Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.Synonyms: MOSC domain-containing protein 2, mitochondrial
Gene ID 54996
NCBI Accession NP_060368
UniProt Q969Z3
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-MARC2 antibody (Mitochondrial Amidoxime Reducing Component 2) (C-Term) (ABIN453749) Western blot analysis of MOSC2 Antibody (C-term) in Hela cell line lysates (35ug/lane...
Background publications Havemeyer, Bittner, Wollers et al.: "Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 34796-802, 2006 (PubMed).

Simpson, Wellenreuther, Poustka et al.: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, 2001 (PubMed).