PPP2R2B antibody (AA 110-139)

Catalog No. ABIN453788

Product Details anti-PPP2R2B Antibody

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Binding Specificity: AA 110-139

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes PPP2R2B.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography followed by peptide Affinity purification.

Immunogen: KLH conjugated synthetic peptide between 110~139 amino acids from the Center region of Human PPP2R2B. Genename: PPP2R2B

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/10-1/50. Flow Cytometry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Alternative Name: PPP2R2B (PPP2R2B Products)

Synonyms: B55BETA antibody, PP2AB55BETA antibody, PP2ABBETA antibody, PP2APR55B antibody, PP2APR55BETA antibody, PR2AB55BETA antibody, PR2ABBETA antibody, PR2APR55BETA antibody, PR52B antibody, PR55-BETA antibody, PR55BETA antibody, SCA12 antibody, Pppr2b2 antibody, 2900026H06Rik antibody, 6330404L05Rik antibody, E130009M08Rik antibody, PP2A-PR55B antibody, PP2A antibody, ppp2r2b-a antibody, ppp2r2c antibody, ppp2r2b antibody, zgc:101861 antibody, PPP2R2B antibody, protein phosphatase 2 regulatory subunit Bbeta antibody, protein phosphatase 2, regulatory subunit B, beta antibody, protein phosphatase 2 regulatory subunit B, beta L homeolog antibody, protein phosphatase 2 regulatory subunit B, beta antibody, protein phosphatase 2, regulatory subunit B, beta b antibody, PPP2R2B antibody, Ppp2r2b antibody, ppp2r2b.L antibody, ppp2r2b antibody, ppp2r2bb antibody

Background: PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.Synonyms: B55-beta isoform, PP2A subunit B B-beta isoform, PR55-beta isoform, R2-beta isoform, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, protein phosphatase 2A 55 kDa regulatory subunit B beta

Molecular Weight: 51710 Da

Gene ID: 5521

NCBI Accession: NP_001120853

UniProt: Q00005

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C