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Retinoblastoma 1 antibody (C-Term)

RB1 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN453807
  • Target See all Retinoblastoma 1 (RB1) Antibodies
    Retinoblastoma 1 (RB1)
    Binding Specificity
    • 32
    • 31
    • 29
    • 24
    • 23
    • 22
    • 20
    • 15
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 291
    • 113
    • 95
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 252
    • 42
    Rabbit
    Clonality
    • 238
    • 56
    Polyclonal
    Conjugate
    • 147
    • 19
    • 17
    • 16
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoblastoma 1 antibody is un-conjugated
    Application
    • 223
    • 132
    • 114
    • 80
    • 79
    • 42
    • 39
    • 36
    • 28
    • 19
    • 19
    • 9
    • 7
    • 6
    • 6
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to RB1.
    Purification
    Saturated Ammonium Sulfate (SAS) precipitation
    Immunogen
    KLH conjugated synthetic peptide selected from the C-terminal region of human RB1
    Top Product
    Discover our top product RB1 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium az
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Retinoblastoma 1 (RB1)
    Alternative Name
    Retinoblastoma-Associated Protein / RB1 (RB1 Products)
    Synonyms
    OSRC antibody, RB antibody, p105-Rb antibody, pRb antibody, pp110 antibody, Rb antibody, Rb-1 antibody, P105-RB antibody, PP110 antibody, RB11 antibody, zgc:154147 antibody, RB transcriptional corepressor 1 antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma 1 antibody, RB1 antibody, RBL1 antibody, Rb1 antibody, rb1 antibody
    Background
    RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
    Gene ID
    5925
    NCBI Accession
    NP_000312
    UniProt
    P06400
    Pathways
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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