XPA antibody (C-Term)

Catalog No. ABIN453876

Product Details anti-XPA Antibody

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to XPAC.

Purification: Affinity chromatography on Protein A

Immunogen: conjugated synthetic peptide selected from the C-term region of human XPA

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Alternative Name: XPA / XPAC (XPA Products)

Synonyms: CG6358 antibody, DhR14 antibody, DhXPA antibody, DmXPA antibody, Dmel\\CG6358 antibody, Dxpa antibody, EG:EG0007.8 antibody, XPAC antibody, XPA_DROME antibody, Xpa antibody, dmXPA antibody, dxpa antibody, XP1 antibody, AI573865 antibody, Xpac antibody, xpac antibody, xxpa antibody, Xeroderma pigmentosum group A-like antibody, XPA, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group A antibody, xeroderma pigmentosum, complementation group A L homeolog antibody, Xpac antibody, XPA antibody, Xpa antibody, xpa.L antibody

Background: XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.Synonyms: DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein

Gene ID: 7507

NCBI Accession: NP_000371

UniProt: P23025

Pathways: DNA Damage Repair