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Activating Transcription Factor 2 (ATF2) antibody

Antigen

Activating Transcription Factor 2 (ATF2)
Synonyms HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Rat (Rattus)
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Catalog no. ABIN459415
Quantity 100µg  (1 mg/ml)  (Variants)
Price 743.71 $   Plus shipping costs $35.00
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anti-Activating Transcription Factor 2 (ATF2) antibody

anti-Activating Transcription Factor 2 (ATF2) antibody (2)

Additional Information
Application Details Images Alternatives Secondary Antibodies Variants back to top

Alternative name ATF2
Format Liquid
Description The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2. Mutations of these sites result in the loss of stress-induced transcription by ATF-2. In addition, mutations at these sites reduce the ability of E1A and Rb to stimulate gene expression via ATF-2.
Synonyms: Rabbit polyclonal to ATF2, Activating transcription factor 2, cAMP response element-binding protein CRE-BP1, HB16, ATF2, 2668, GDNF, 142623, P39905, ATF1, ATF2, HFB1-GDNF,
Specificity ATF2 (D67/49) pAb detects endogenous levels of ATF2 protein.
Molecular Weight 52 kDa

Application Details
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Application Notes WB: 1:500-1:1000 IHC: 1:50-1:200 IP: 1:50-1:200
Concentration 1 mg/ml
Purity > 95% (by SDS-PAGE).
Purification The pAb was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies Variants back to top

Alternatives for antigen "Activating Transcription Factor 2 (ATF2)", type "Antibodies"
Hosts Rabbit (150), Mouse (16), Goat (4), Sheep (3)
Reactivities Human (171), Mouse (Murine) (102), Rat (Rattus) (90), Cow (Bovine) (3), Dog (Canine) (3), Pig (Porcine) (2), Rabbit (2), Horse (Equine) (1)
Applications Western Blotting (WB) (108), Immunohistochemistry (IHC) (64), Immunofluorescence (IF) (49), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (47), Enzyme Immunoassay (EIA) (32), Immunoprecipitation (IP) (32), ELISA (24), Flow Cytometry (FACS) (19), Dot Blot (Dot) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes Ab-112 or 94 (5), Ab-62 or 44 (5), Ab-69 or 51 (5), Ab-71 or 53 (5), Ab-73 or 55 (5), pSer112 or 94 (5), pSer62 or 44 (5), pThr69 or 51 (5), pThr69/51 (5), pThr71 or 53 (5), pThr73 or 55 (5), pSer62/44 (4), pThr71/53 (4), pSer112/94 (3), pThr73/55 (3), S44 (2), S94 (2), S322 (1), pSer112, pSer94 (1), pSer340, pSer322 (1), pSer44 (1), pSer472 (1), pSer62, pSer44 (1), pSer94 (1), pThr51 (1), pThr69, pThr51 (1), pThr69/51 + pThr71/53 (1), pThr71 (1), pThr79, pThr51 (1)