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Cytokeratin 8 (KRT8) antibody
| Antigen | Cytokeratin 8 (KRT8) |
| Synonyms | K8, KO, CK8, CYK8, K2C8, CARD2, K18, CYK18, Card2, EndoA, Krt2-8, Krt-2.8, AA960620, AL022697, AU019895, MGC118110, KRT2-8 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Rat (Rattus) |
| Application |
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
|
| Catalog no. | ABIN459928 |
| Quantity | 100µg (1 mg/ml) (Variants) |
| Price | 743.71 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | Cytokeratin 8 |
| Format | Liquid |
| Description |
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations o the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa. Synonyms: KRT8, CARD2, CK-8, CK8, CYK8, CYTOKERATIN-8, K2C8, K8, KERATIN-8, KO |
| Specificity | K8 (G427) pAb detects endogenous levels of K8 protein. |
| Molecular Weight | 50.0 kDa |
Application Details
| Application Notes | WB: 1:500-1:1000 IHC: 1:50-1:200 IF: 1:50-1:200 |
| Concentration | 1 mg/ml |
| Purity | > 95% (by SDS-PAGE). |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Cytokeratin 8 (KRT8)", type "Antibodies"
| Hosts | Mouse (46), Rabbit (45), Guinea Pig (1) |
| Reactivities | Human (76), Mouse (Murine) (11), Rat (Rattus) (11), Cow (Bovine) (8), Pig (Porcine) (7), Sheep (Ovine) (6), Rabbit (5), Hamster (3), None (3), Mammalian (1) |
| Applications | Western Blotting (WB) (57), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (51), Immunofluorescence (IF) (30), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Immunohistochemistry (IHC) (16), Enzyme Immunoassay (EIA) (9), Immunoprecipitation (IP) (8), ELISA (Detection) (5), ELISA (4), Immunocytochemistry (ICC) (4), Flow Cytometry (FACS) (2) |
| Conjugates | Biotin (2), FITC (1), HRP (1) |
| Epitopes | C-Term (4), pSer74 (4), pSer73 (1) |
