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Antibodies
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anti-Mucin 1, Cell Surface Associated (MUC1) antibody
Mucin 1, Cell Surface Associated (MUC1) antibody
| Antigen |
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| Synonyms |
EMA, PEM, PUM, KL-6, MAM6, PEMT, CD227, H23AG, MGC188069, MUC1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (IHC), Immunofluorescence (IF)
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| Catalog no. |
ABIN460098 |
| Quantity |
100µg (1 mg/ml) |
| Price |
743.71 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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Mucin 1
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Format
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Liquid
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Description
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MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.
Synonyms: MUC1, CD227, EMA, EPISIALIN, H23AG, MAM6, MUC-1, PEM, PEMT, PUM
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Specificity
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Mucin 1 (S1239) pAb detects endogenous levels of Mucin 1 protein.
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Application Notes
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IHC: 1:50-1:200 IF:1:50-1:200
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Concentration
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1 mg/ml
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Purity
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> 95% (by SDS-PAGE).
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Purification
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Buffer
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1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
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Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Restrictions
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For Research Use only
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Alternatives for antigen "Mucin 1, Cell Surface Associated (MUC1)", type "Antibodies"
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Hosts
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Mouse (23), Rabbit (2), Hamster (1), Rat (1)
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Reactivities
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Human (23)
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Applications
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (10), Immunohistochemistry (IHC) (7), Western Blotting (WB) (5), Immunofluorescence (IF) (4), Enzyme Immunoassay (EIA) (3), ELISA (1), Flow Cytometry (FACS) (1)
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Epitopes
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Ab-5 (1), C-Term (1), Core (1), RPAP (1), pTyr1203 (1)
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