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Cyclin D1 (CCND1) antibody
| Antigen | Cyclin D1 (CCND1) |
| Synonyms |
BCL1, PRAD1, U21B31, D11S287E, cD1, Cyl-1, bcl-1, AI327039, DIP1, GCIP, Maid, SECC-8, SSEC-8, AU022347, cb161, cycd1, fb52e01, fc83a12, id:ibd1198, wu:fb52e01, wu:fc83a12, MGC109078, ccnd1b, MGC52909, ...
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| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Rat (Rattus) |
| Application |
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
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| Catalog no. | ABIN460104 |
| Quantity | 100µg (1 mg/ml) (Variants) |
| Price | 743.71 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | Cyclin D1 |
| Format | Liquid |
| Description |
The proliferation of eukaryotic cells is controlled at specific points in the cell cycle, particularly at the G1 to S and the G2 to M transitions. It is well established that the Cdc2 p34-cyclin B protein kinase plays a critical role in the G2 to M transition while cyclin A associates with Cdk2 p33 and functions in S phase. Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors. Synonyms: CCND1, BCL1, D11S287E, PRAD1, U21B31 |
| Specificity | Cyclin D1 (L283) pAb detects endogenous levels of Cyclin D1 protein. |
| Molecular Weight | 33 kDa |
| Synonyms | BCL1, PRAD1, U21B31, D11S287E, cD1, Cyl-1, bcl-1, AI327039, DIP1, GCIP, Maid, SECC-8, SSEC-8, AU022347, cb161, cycd1, fb52e01, fc83a12, id:ibd1198, wu:fb52e01, wu:fc83a12, MGC109078, ccnd1b, MGC52909, MGC132138, ccnd1, MGC53090, bcl1, prad1, u21b31, MGC69515, d11s287e, CCND1, ccndbp1, MGC137744, ZHM, CCNDBP1, MGC133757, DKFZp468E2216, DKFZp469C1216, DKFZp469H0317 |
Application Details
| Application Notes | WB: 1:500-1:1000 IHC: 1:50-1:200 |
| Concentration | 1 mg/ml |
| Purity | > 95% (by SDS-PAGE). |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Cyclin D1 (CCND1)", type "Antibodies"
| Hosts | Rabbit (51), Mouse (27) |
| Reactivities | Human (67), Rat (Rattus) (31), Mouse (Murine) (28), Monkey (3), Dog (Canine) (2), Guinea Pig (2), Rabbit (2), Cow (Bovine) (1), Orang-Utan (1), Sheep (Ovine) (1) |
| Applications | Western Blotting (WB) (63), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (31), Immunoprecipitation (IP) (20), Immunohistochemistry (Frozen Sections) (IHC (fro)) (13), Immunohistochemistry (IHC) (13), ELISA (12), Enzyme Immunoassay (EIA) (9), Flow Cytometry (FACS) (8), Immunocytochemistry (ICC) (4), Immunofluorescence (IF) (4), ELISA (Detection) (3), Dot Blot (Dot) (1), Functional Studies (Func) (1) |
| Epitopes | C-Term (3), N-Term (2), Ab-286 (1), Center (1), S90 (1), pThr286 (1) |
