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beta-Catenin (CTNNB1) antibody

Antigen

beta-Catenin (CTNNB1)

Synonyms
CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1) ... show more
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Rat (Rattus)

Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Catalog no. ABIN460259
Quantity 100µg  (1 mg/ml)  (Variants)
Price 743.71 $   Plus shipping costs $35.00
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Additional Information

Alternative name Catenin-beta1
Format Liquid
Description Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonistmediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first are the second messenger-regulated kinases such as c-AMP dependent protein kinase A and protein kinase C. The second are the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase, GRK 1, two forms of beta-adrenergic receptor kinase, GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.
Synonyms: CTNNB1, BETA-CATENIN, CTNNB, PRO2286
Specificity Catenin-beta1 (F660) pAb detects endogenous levels of Catenin-beta1 protein.
Molecular Weight 85.0 kDa
Synonyms CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Application Details

Application Notes WB: 1:500-1:1000 IF: 1:50-1:200 IHC: 1:50-1:200
Concentration 1 mg/ml
Purity > 95% (by SDS-PAGE).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "beta-Catenin (CTNNB1)", type "Antibodies"
Hosts Rabbit (148), Mouse (42)
Reactivities Human (173), Mouse (Murine) (114), Rat (Rattus) (104), Chicken (18), Dog (Canine) (6), Hamster (2), Xenopus laevis (2), Monkey (1)
Applications Western Blotting (WB) (169), Immunofluorescence (IF) (55), Immunoprecipitation (IP) (47), Enzyme Immunoassay (EIA) (43), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (43), Immunohistochemistry (IHC) (35), ELISA (27), Flow Cytometry (FACS) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (12), Dot Blot (Dot) (7), Immunocytochemistry (ICC) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (5), FITC (2), HRP (2), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitopes pSer37 (9), pSer33 (8), Ab-33 (5), Ab-37 (5), Ab-41/45 (5), C-Term (5), pThr41/Ser45 (5), pThr41/pSer45 (4), Ab-654 (3), pTyr654 (3), pTyr86 (3), exon 3 (2), pSer33/37 (2), Ab-489 (1), Core (1), dep27-37 (1), dep35-50 (1), pSer45 (1), pTyr489 (1)