N-Cadherin (CD325) antibody

Antigen: N-Cadherin (CD325)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat (Rattus)

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Catalog no.: ABIN460388

Additional Information

Alternative name: N-cadherin

Format: Liquid

Description: Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2-terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxyterminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as beta-catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P-cadherin and cadherin-5.
Synonyms: Rabbit polyclonal to N Cadherin, Neural cadherin, N-cadherin, CDw325, CD325 antigen, N Cadherin, 1000, CDH2, 114020, P19022, CDHN, NCAD,

Specificity: N-cadherin (W745) pAb detects endogenous levels of N-cadherin protein.

Molecular Weight: 140.0 kDa

Application Details

Application Notes: WB: 1:500-1:1000 IHC: 1:50-1:200 IF: 1:50-1:200

Concentration: 1 mg/ml

Purity: > 95% (by SDS-PAGE).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Restrictions: For Research Use only

Images

anti-N-Cadherin (CD325) antibody

anti-N-Cadherin (CD325) antibody (Image 2)