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A Kinase (PRKA) Anchor Protein 1 (AKAP1) antibody
| Antigen | A Kinase (PRKA) Anchor Protein 1 (AKAP1) |
| Synonyms | AKAP, PRKA1, AKAP84, AKAP121, AKAP149, D-AKAP1, MGC1807, SAKAP84, Akap, C76494, C81186, DAKAP1, S-AKAP84, AKAP1, akap1, fa08b04, MGC162884, wu:fa08b04, Akap84 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
|
| Catalog no. | ABIN460541 |
| Quantity | 100µg (1 mg/ml) (Variants) |
| Price | 743.71 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | AKAP 149 |
| Format | Liquid |
| Description |
The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization. Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), which are a network of proteins located on the internal surfaces of excitatory synapses. Synonyms: AKAP1 |
| Specificity | AKAP 149(N306) pAb detects endogenous levels of AKAP 149 protein. |
| Molecular Weight | 90 kDa |
Application Details
| Application Notes | WB: 1:500-1:1000 IHC: 1:50-1:200 IF: 1:50-1:200 |
| Concentration | 1 mg/ml |
| Purity | > 95% (by SDS-PAGE). |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Restrictions | For Research Use only |
Images
| anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) antibody anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) antibody (Image 2) |
Alternatives
Alternatives for antigen "A Kinase (PRKA) Anchor Protein 1 (AKAP1)", type "Antibodies"
| Hosts | Rabbit (4), Mouse (3) |
| Reactivities | Human (6) |
| Applications | Western Blotting (WB) (7), ELISA (2), ELISA (Detection) (2), Immunofluorescence (IF) (2), Enzyme Immunoassay (EIA) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1) |
