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Laminin, alpha 4 (LAMa4) antibody
| Antigen | Laminin, alpha 4 (LAMa4) |
| Synonyms | LAMA3, LAMA4*-1, DKFZp686D23145, RGD1560062, si:dkey-119m7.3, si:busm1-189a20.2 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
|
| Catalog no. | ABIN460555 |
| Quantity | 100µg (1 mg/ml) |
| Price | 743.71 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | Laminin alpha-4 |
| Format | Liquid |
| Description |
Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cellassociated extracellular matrices (ECMs)) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans.Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of alpha, beta, and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human laminin alpha-4 gene maps to chromosome 6q21 and is expressed in adult heart, lung, ovary, small and large intestines, liver, and placenta. Synonyms: LAMA4 |
| Specificity | Laminin alpha-4 (A511) pAb detects endogenous levels of Laminin alpha-4 protein. |
| Molecular Weight | 203 kDa |
Application Details
| Application Notes | WB: 1:500-1:1000 IHC: 1:50-1:200 IF: 1:50-1:200 |
| Concentration | 1 mg/ml |
| Purity | > 95% (by SDS-PAGE). |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Laminin, alpha 4 (LAMa4)", type "Antibodies"
| Hosts | Mouse (9), Rabbit (3) |
| Reactivities | Human (12), Mouse (Murine) (2) |
| Applications | Western Blotting (WB) (10), ELISA (Detection) (5), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunoprecipitation (IP) (3), Immunofluorescence (IF) (2), ELISA (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1) |
