Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2) antibody

Antigen: Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2)

Synonyms: CD312, DKFZp781B135, EMR2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN460697

Additional Information

Alternative name: EMR2

Format: Liquid

Description: The epidermal growth factor (EGF) family constitutes a group of class B, G protein-coupled receptors, which includes CD97 and EMR2. EMR2 is a member of the EGF-TM7 receptor subfamily. EGF-TM7 receptors are a family of class B, seven-span transmembrane (TM7) receptors predominantly expressed by cells of the immune system. Within the TM7 superfamily, the molecular structure and ligand-binding properties of EGF-TM7 receptors are unique. Derived from the processing of a single polypeptide, they are expressed at the cell surface as heterodimers consisting of a large extracellular region associated with a TM7 moiety. Through a variable number of N-terminal EGF-like domains, EGF-TM7 receptors interact with cellular ligands such as CD55 and chondroitin sulfate. EMR2 is a heptahelical molecule predominantly expressed on cells of the immune system such as leukocytes. EMR2 is proteolytically cleaved into two separate subunits: a seven-transmembrane subunit, and an extracellular alpha subunit.
Synonyms: EMR2, CD312, DKFZP781B135

Specificity: EMR2 (L808) pAb detects endogenous levels of EMR2 protein.

Molecular Weight: 85 kDa

Application Details

Application Notes: WB: 1:500-1:1000 IF: 1:50-1:200

Concentration: 1 mg/ml

Purity: > 95% (by SDS-PAGE).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Restrictions: For Research Use only

Images

anti-Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2) antibody