CNPase (CNP) antibody
| Antigen |
|
| Synonyms |
CNP1, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, CNP, sb:cb662, wu:fd44a05, wu:fi35d08, si:ch73-158e11.4, DKFZp469F1421 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
|
| Catalog no. |
ABIN460940 |
| Quantity |
100µg (1 mg/ml) (Variants) |
| Price |
743.71 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Alternative name
|
CNPase
|
|
Format
|
Liquid
|
|
Description
|
CNPase (2',3'-Cyclic Nucleotide 3'-Phosphodiesterase) exists in two forms: 46kDa (CNP1) and 48kDa (CNP2). It is expressed at high levels by oligodendrocytes in the central nervous system and by Schwann cells in the peripheral nervous system and is virtual absent in other cell types. CNPase activity is decreased in demyelinating diseases such as multiple sclerosis. CNPase gene is localized to chromosome 17q21, very near the BRCA 1 familial breast cancer gene.
|
|
Specificity
|
CNPase (A108) pAb detects endogenous levels of CNPase protein.
|
|
Molecular Weight
|
48 kDa
|
|
Application Notes
|
WB: 1:500-1:1000 IHC: 1:50-1:200
|
|
Concentration
|
1 mg/ml
|
|
Purity
|
> 95% (by SDS-PAGE).
|
|
Purification
|
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
|
|
Buffer
|
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
|
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "CNPase (CNP)", type "Antibodies"
|
Hosts
|
Rabbit (12), Mouse (4), Chicken (1)
|
|
Reactivities
|
Human (16), Mouse (Murine) (9), Rat (Rattus) (8), Rabbit (2), Sheep (Ovine) (2), Cat (Feline) (1), Cow (Bovine) (1), Dog (Canine) (1), Pig (Porcine) (1)
|
|
Applications
|
Western Blotting (WB) (15), ELISA (Detection) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), ELISA (2), Enzyme Immunoassay (EIA) (2), Immunofluorescence (IF) (2), ELISA (Capture) (1), Immunoprecipitation (IP) (1)
|
|
Epitopes
|
AA 68-84 (1)
|