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ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) antibody
| Antigen | ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) |
| Synonyms | MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, CDw338, EST157481, MGC102821, Bcrp1, AI428558, ABCG2, MGC127688, bcrp |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB)
|
| Catalog no. | ABIN460959 |
| Quantity | 100µg (1 mg/ml) (Variants) |
| Price | 743.71 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | ABCG2 |
| Format | Liquid |
| Description |
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC halftransporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells. Synonyms: ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CDW338, EST157481, MGC102821, MRX, MXR, MXR1 |
| Specificity | ABCG2 (N338) pAb detects endogenous levels of ABCG2 protein. |
| Molecular Weight | 72 kDa |
Application Details
| Application Notes | WB: 1:500-1:1000 IHC: 1:50-1:200 |
| Concentration | 1 mg/ml |
| Purity | > 95% (by SDS-PAGE). |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Restrictions | For Research Use only |
Images
| anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) antibody anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) antibody (Image 2) |
Alternatives
Alternatives for antigen "ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2)", type "Antibodies"
| Hosts | Rabbit (34), Mouse (28), Rat (4) |
| Reactivities | Human (58), Mouse (Murine) (27), Rat (Rattus) (17), Cow (Bovine) (2), Monkey (2), Dog (Canine) (1), Escherichia Coli (E. Coli) (1) |
| Applications | Flow Cytometry (FACS) (40), Western Blotting (WB) (36), Immunofluorescence (IF) (28), Immunohistochemistry (Frozen Sections) (IHC (fro)) (14), ELISA (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Enzyme Immunoassay (EIA) (6), Immunohistochemistry (IHC) (4), Immunocytochemistry (ICC) (3), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1) |
| Conjugates | Biotin (4), PE (3), FITC (2), APC (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | C-Term (2), Center (2) |
