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Keratin 19 (KRT19) antibody
| Antigen | Keratin 19 (KRT19) |
| Synonyms | K19, CK19, K1CS, MGC15366, EndoC, Krt1-19, AI663979, Krt-1.19, MGC25344, Ka19, MGC124534, MGC156553, k19, ck19, k1cs, krt9, krt15, MGC76282, KRT19, GK-19, MGC83069, LOC514812, MGC154386, DKFZp469N0613 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Rat (Rattus) |
| Application |
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
|
| Catalog no. | ABIN461008 |
| Quantity | 100µg (1 mg/ml) (Variants) |
| Price | 743.71 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | Cytokeratin 19 |
| Format | Liquid |
| Description |
This protein is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7. Synonyms: CK 18, CK18, CYK18, Cytokeratin 18, Cytokeratin endo B, Cytokeratin18, K18, Keratin 18, Keratin D, Keratin type I cytoskeletal 18, Keratin18, Kerd, KRT18 |
| Specificity | Cytokeratin 19 (L349) pAb detects endogenous levels of Cytokeratin 19 protein. |
| Molecular Weight | 40 kDa |
Application Details
| Application Notes | WB: 1:500-1:1000 IHC: 1:50-1:200 |
| Concentration | 1 mg/ml |
| Purity | > 95% (by SDS-PAGE). |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Keratin 19 (KRT19)", type "Antibodies"
| Hosts | Mouse (68), Rabbit (32), Guinea Pig (1) |
| Reactivities | Human (86), Rat (Rattus) (10), Mouse (Murine) (9), Monkey (3), None (3), Cow (Bovine) (2), Dog (Canine) (2), Amphibian (1), Chicken (1), Guinea Pig (1) |
| Applications | Western Blotting (WB) (68), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (57), Immunofluorescence (IF) (31), Immunohistochemistry (IHC) (23), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), ELISA (17), Enzyme Immunoassay (EIA) (16), Immunoprecipitation (IP) (16), Flow Cytometry (FACS) (8), Immunocytochemistry (ICC) (8), ELISA (Detection) (5), Dot Blot (Dot) (1) |
| Conjugates | Biotin (3), Alexa Fluor 488 (1), FITC (1), HRP (1) |
| Epitopes | C-Term (3), AA 311-335 (1), AA 312-335 (1), Center (1), S46 (1), pS46 (1) |
