Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) antibody

Antigen: Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2)

Synonyms: GLUR2, GLURB, HBGR2, GluR-K2, GRIA2, GluR-2, GluR-B, MGC139795, ATGLR2, ATGLR3.1, F5J6.2, F5J6_2, GLR2, GLR3.1, GLUTAMATE RECEPTOR 2, ATGLR3.2, ATGLUR2, F23E12.150, F23E12_150, GLR3.2, GLUTAMATE RECEPTOR 3.2, DKFZp459F083, GLUH1, GLUR1, GLURA, HBGR1, MGC133252, Glr1, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, AI853806, 2900051M01Rik, gluR-A, GluA2, Glur2, Glur-2, GluR2, gluR-B

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat (Rattus)

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Catalog no.: ABIN461107

Additional Information

Alternative name: GluR2

Format: Liquid

Description: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.

Specificity: GluR2 (Y873) pAb detects endogenous levels of GluR2 protein.

Molecular Weight: 99 kDa

Synonyms: GLUR2, GLURB, HBGR2, GluR-K2, GRIA2, GluR-2, GluR-B, MGC139795, ATGLR2, ATGLR3.1, F5J6.2, F5J6_2, GLR2, GLR3.1, GLUTAMATE RECEPTOR 2, ATGLR3.2, ATGLUR2, F23E12.150, F23E12_150, GLR3.2, GLUTAMATE RECEPTOR 3.2, DKFZp459F083, GLUH1, GLUR1, GLURA, HBGR1, MGC133252, Glr1, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, AI853806, 2900051M01Rik, gluR-A, GluA2, Glur2, Glur-2, GluR2, gluR-B

Application Details

Application Notes: WB: 1:500-1:1000 IHC: 1:50-1:200 IF:1:50-1:200

Concentration: 1 mg/ml

Purity: > 95% (by SDS-PAGE).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Restrictions: For Research Use only

Images

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) antibody

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) antibody (Image 2)