ALDH1A1 antibody (Center)

Catalog No. ABIN356973

Product Details anti-ALDH1A1 Antibody

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ALDH1A1 at Center.

Purification: Purified

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ALDH1A1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunofluorescence 1: 10 - 1: 50. Immunohistochemistry 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: ALDH1 (ALDH1A1 Products)

Synonyms: ALDC antibody, ALDH-E1 antibody, ALDH1 antibody, ALDH11 antibody, PUMB1 antibody, RALDH1 antibody, AL1A1 antibody, aldc antibody, aldh-e1 antibody, aldh1 antibody, aldh11 antibody, pumb1 antibody, raldh1 antibody, GGADHR antibody, ALDH1A1 antibody, ALDDH antibody, Ahd2 antibody, Aldh1 antibody, Aldh2 antibody, Ahd-2 antibody, Aldh1a2 antibody, E1 antibody, Raldh1 antibody, Aldh1a1 antibody, ALHDII antibody, RALDH 1 antibody, RalDH1 antibody, aldehyde dehydrogenase 1 family member A1 antibody, aldehyde dehydrogenase 1 family, member A1 antibody, aldehyde dehydrogenase 1 family member A1 L homeolog antibody, aldehyde dehydrogenase family 1, subfamily A1 antibody, aldehyde dehydrogenase antibody, retinal dehydrogenase 1 antibody, ALDH1A1 antibody, aldh1a1 antibody, Aldh1a1 antibody, aldh1a1.L antibody, aldH1 antibody, LOC100732581 antibody, LOC101822890 antibody

Background: ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.Synonyms: ALDC, ALDH-E1, ALDH1A1, ALHDII, Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, PUMB1, RALDH1, Retinal dehydrogenase 1

Molecular Weight: 54731 Da

Gene ID: 216, 9606

UniProt: P00352

Pathways: Dopaminergic Neurogenesis