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PCDH11Y antibody (AA 918-929)

PCDH11Y Reactivity: Human ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN466846
  • Target See all PCDH11Y Antibodies
    PCDH11Y (Protocadherin 11 Y-Linked (PCDH11Y))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 918-929
    Reactivity
    Human
    Host
    • 4
    • 3
    • 1
    Goat
    Clonality
    • 5
    • 3
    Polyclonal
    Conjugate
    • 8
    This PCDH11Y antibody is un-conjugated
    Application
    • 7
    • 6
    ELISA
    Specificity
    Human PCDH11Y. This antibody is expected to recognize all reported Y-linked isoforms (NP_116753.1, NP_116754.1, NP_116755.1) and all reported X-linked isoforms (NP_055337.1, NP_055337.1, NP_116750.1, NP_116751.1).
    Predicted Reactivity
    Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon (100%) Gorilla, Mouse, Rat, Hamster, Bovine, Horse, Pig, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (92%) Dog (83%).
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic peptide C-KYNWVTTPTTFK from an internal region of human PCDH11Y (NP_116753.1, NP_116754.1, NP_116755.1, NP_055337.1, NP_055337.1, NP_116750.1, NP_116751.1). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon (100%), Gorilla, Mouse, Rat, Hamster, Bovine, Horse, Pig, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (92%), Dog (83%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product PCDH11Y Primary Antibody
  • Application Notes
    Approved: Peptide-ELISA

    Usage: Western Blot: Preliminary experiments gave an approx 75kD band in Human Brain (Amygdala, Hippocampus, Substantia nigra) lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kD according to NP_116753.1 and of 113kD according to NP_055337.1, the smallest reported isoforms. The 75kD band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    PCDH11Y (Protocadherin 11 Y-Linked (PCDH11Y))
    Alternative Name
    PCDH11Y / Protocadherin Y (PCDH11Y Products)
    Synonyms
    PCDH-PC antibody, PCDH22 antibody, PCDHY antibody, protocadherin 11 Y-linked antibody, PCDH11Y antibody
    Background
    Name/Gene ID: PCDH11Y

    Synonyms: PCDH11Y, PCDH22, PCDHY, Protocadherin Y, Protocadherin-PC, Protocadherin prostate cancer, Protocadherin-11 Y-linked, PCDH11, Protocadherin 11 Y-linked, Protocadherin 22, Protocadherin-11, PCDH-PC, PCDH-Y, Protocadherin-22
    Gene ID
    83259
    NCBI Accession
    NP_116753, NP_116754, NP_116755, NP_055337, NP_116750, NP_116751
    UniProt
    Q9BZA8
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