SHANK3 antibody (AA 840-857)

Catalog No. ABIN467005

Product Details anti-SHANK3 Antibody

Target: SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))

Binding Specificity: AA 840-857

Reactivity: Rat, Human, Mouse, Cow, Horse, Hamster, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This SHANK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: Detects ~190 kD protein.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Bovine, Horse (100%) Rabbit, Opossum (94%).

Purification: Protein G purified from tissue culture supernatant

Immunogen: Synthetic peptide amino acids 840-857 PEKLPGSLRKGIPRTKSV) of rat Shank3 (also known as SH3 and multiple ankyrin repeat domains protein 3, proline-rich synapse- associated protein 2, ProSAP2 and SPANK-2, accession number Q9JLU4). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Bovine, Horse (100%), Rabbit, Opossum (94%).

Type of Immunogen: Synthetic peptide

Clone: S69-46

Isotype: IgG2b

Application Details

Application Notes: Approved: ICC (0.1 - 1 μg/mL), IHC (0.1 - 1 μg/mL), IP (1 - 10 μg/mL), WB (1 - 10 μg/mL)

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 50 % glycerol, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for SHANK3

Target: SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))

Alternative Name: SHANK3 (SHANK3 Products)

Synonyms: DEL22q13.3 antibody, PROSAP2 antibody, PSAP2 antibody, SCZD15 antibody, SPANK-2 antibody, Prosap2 antibody, AI841104 antibody, Shank3b antibody, SH3 and multiple ankyrin repeat domains 3 antibody, SH3 and multiple ankyrin repeat domains protein 3 antibody, SHANK3 antibody, shank3 antibody, Shank3 antibody

Background: Name/Gene ID: SHANK3

Synonyms: SHANK3, DEL22q13.3, KIAA1650, SPANK-2, PROSAP2, PSAP2, SCZD15

Gene ID: 85358

UniProt: Q9BYB0

Pathways: Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity