GSK3 alpha antibody (AA 203-219)
-
- Target See all GSK3 alpha (GSK3a) Antibodies
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
-
Binding Specificity
- AA 203-219
-
Reactivity
- Drosophila melanogaster
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This GSK3 alpha antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunocytochemistry (ICC)
- Specificity
- Recognizes Glycogen Synthase Kinase 3 (GSK3). Due to extremely high conservation among the known enzymes of many different species, should cross-react with nearly all species homologues. Species cross-reactivity: Mouse, rat, S. pombe, Dictyostelium and human.
- Predicted Reactivity
- Percent identity by BLAST analysis: Drosophila, Mosquito (100%) Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (88%).
- Purification
- Protein G purified
- Immunogen
-
Synthetic peptide corresponding to aa203-219 (18aa, C-KQLLHGEPNVSYICSRY) derived from a region of the catalytic domain (between subdomain VII and VIII) of the Drosophila GSK-3/ shaggy enzyme (ovalbumin coupled). Percent identity by BLAST analysis: Drosophila, Mosquito (100%), Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (88%).
Type of Immunogen: Synthetic peptide - Isotype
- IgG1
- Top Product
- Discover our top product GSK3a Primary Antibody
-
-
- Application Notes
-
Approved: ICC (10 μg/mL), WB (0.5 - 2 μg/mL)
Usage: Suitable for use in Western Blot and Immunocytochemistry. Proteins were visualized using an IgG (HRP) goat anti-mouse and a chemiluminescence detection system. Immunocytochemistry: 10 μg/mL. Demonstrated positive immunostaining for GSK3 in L6 cells fixed with acetone. Positive control: J9000: Jurkat Cell. - Comment
-
Target Species of Antibody: Drosophila
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
-
- Target
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- Alternative Name
- GSK3A / GSK3 Alpha (GSK3a Products)
- Synonyms
- 2700086H06Rik antibody, GSK3A antibody, GSK-3[a] antibody, GSK-3[b] antibody, GSK3 antibody, gsk3a antibody, xgsk3 antibody, glycogen synthase kinase 3 alpha antibody, glycogen synthase kinase 3 alpha b antibody, glycogen synthase kinase 3 alpha S homeolog antibody, GSK3A antibody, Gsk3a antibody, gsk3a antibody, gsk3ab antibody, gsk3a.S antibody, Bm1_31380 antibody
- Background
-
Name/Gene ID: GSK3A
Subfamily: GSK-3
Family: Protein Kinase
Synonyms: GSK3A, GSK-3 alpha, GSK3 alpha - Gene ID
- 2931
- UniProt
- P49840
- Pathways
- PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
-