TLN1 antibody (AA 1695-1708)

Catalog No. ABIN477971

Product Details anti-TLN1 Antibody

Target: TLN1 (Talin 1 (TLN1))

Binding Specificity: AA 1695-1708

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Rabbit, Monkey, Bat, Horse

Host: Goat

Clonality: Polyclonal

Conjugate: This TLN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human TLN1 / Talin. This antibody is not expected to cross-react with the highly similar protein Talin 2.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig, Opossum, Platypus (100%) Chicken, Xenopus (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-QEALHTQMLTAVQE from an internal region of human TLN1 / Talin (NP_006280.3). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig, Opossum, Platypus (100%), Chicken, Xenopus (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA, WB (1 - 3 μg/mL)

Usage: Western Blot: A >250kD band observed in Human Peripheral Mononucleocyte lysates (calculated MW of 270kD according to NP_006280.3). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 110kD. This band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TLN1

Target: TLN1 (Talin 1 (TLN1))

Alternative Name: TLN1 / Talin (TLN1 Products)

Synonyms: ILWEQ antibody, TLN antibody, Tln antibody, sb:cb854 antibody, wu:fb05c02 antibody, TLN1 antibody, talin-1 antibody, tln antibody, talin 1 antibody, talin 1 L homeolog antibody, Talin 1 antibody, talin-1 antibody, TLN1 antibody, Tln1 antibody, tln1 antibody, tln1.L antibody, Bm1_56490 antibody, LOC100380665 antibody

Background: Name/Gene ID: TLN1

Synonyms: TLN1, KIAA1027, TLN, Talin-1, ILWEQ, Talin, Talin 1

Gene ID: 7094

NCBI Accession: NP_006280

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location