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JAK2 antibody (pTyr570)

JAK2 Reactivity: Human, Rat, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN481941
  • Target See all JAK2 Antibodies
    JAK2 (Janus Kinase 2 (JAK2))
    Binding Specificity
    • 37
    • 34
    • 16
    • 16
    • 13
    • 12
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 541-590, pTyr570
    Reactivity
    • 178
    • 101
    • 97
    • 18
    • 18
    • 3
    • 2
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 180
    • 6
    • 2
    Rabbit
    Clonality
    • 164
    • 24
    Polyclonal
    Conjugate
    • 93
    • 16
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This JAK2 antibody is un-conjugated
    Application
    • 136
    • 86
    • 62
    • 61
    • 29
    • 27
    • 26
    • 25
    • 17
    • 13
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity

    JAK2 (Phospho-Tyr570) Antibody detects endogenous levels of JAK2 only when phosphorylated at Tyr570.

    PhosphorylationH:Y570 M:Y570 R:Y570

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human JAK2 around the phosphorylation site of Tyr570.
    Isotype
    IgG
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    Discover our top product JAK2 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 ELISA: 1:1000
    Comment

    Unigene-Number: Hs.656213 (NCBI Gene Symbol: JAK2)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Target
    JAK2 (Janus Kinase 2 (JAK2))
    Alternative Name
    JAK2 (JAK2 Products)
    Synonyms
    JAK2bCA antibody, jak2 antibody, JTK10 antibody, THCYT3 antibody, AI504024 antibody, C81284 antibody, Fd17 antibody, JAK-2 antibody, Janus kinase 2b antibody, Janus kinase 2 antibody, jak2b antibody, JAK2 antibody, Jak2 antibody
    Background

    Synonyms: JAK-2, JAK2, Janus kinase 2, kinase Jak2

    NCBI Gene Symbol: JAK2

    Molecular Weight
    130 kDa
    Gene ID
    3717
    OMIM
    147796
    UniProt
    O60674
    Pathways
    JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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