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Caspase 6 antibody (Cleaved-Asp162)

CASP6 Reactivity: Human, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN486701
  • Target See all Caspase 6 (CASP6) Antibodies
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Binding Specificity
    • 26
    • 16
    • 15
    • 12
    • 11
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-179, Cleaved-Asp162
    Reactivity
    • 138
    • 78
    • 36
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 160
    • 10
    • 1
    Rabbit
    Clonality
    • 149
    • 22
    Polyclonal
    Conjugate
    • 76
    • 16
    • 13
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    This Caspase 6 antibody is un-conjugated
    Application
    • 138
    • 68
    • 61
    • 41
    • 40
    • 30
    • 26
    • 17
    • 14
    • 13
    • 11
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity

    Caspase 6 (Cleaved-Asp162) Antibody detects endogenous levels of fragment of activated Caspase 6 resulting from cleavage adjacent to Asp162.

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human Caspase 6.
    Isotype
    IgG
    Top Product
    Discover our top product CASP6 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
    Comment

    Unigene-Number: Hs.654616 (NCBI Gene Symbol: CASP6)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Yashiro, Qiu, Hasegawa, Zhang, Matsuzaki, Hirakawa: "An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells." in: British journal of cancer, (2011) (PubMed).

  • Target
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Alternative Name
    Caspase 6 (CASP6 Products)
    Synonyms
    xCaspase-6 antibody, mch2 antibody, caspase-6 antibody, zgc:112960 antibody, CASP6 antibody, casp6 antibody, Mch2 antibody, mCASP-6 antibody, MCH2 antibody, caspase 6 L homeolog antibody, caspase 6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, group XIIA secretory phospholipase A2 antibody, caspase-6 antibody, casp6.L antibody, casp6 antibody, CASP6 antibody, CpipJ_CPIJ017008 antibody, Casp6 antibody
    Background

    Synonyms: ICE6, MCH2, apoptotic protease Mch-2, caspase-6

    NCBI Gene Symbol: CASP6

    Molecular Weight
    20 and 35 kDa
    Gene ID
    839
    OMIM
    601532
    UniProt
    P55212
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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