Homeobox C5 antibody (Middle Region)

Catalog No. ABIN486827

Product Details anti-Homeobox C5 Antibody

Target: Homeobox C5 (HOXC5)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Homeobox C5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WMTKLHMSHE TDGKRSRTSY TRYQTLELEK EFHFNRYLTR RRRIEIANNL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HOXC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXC5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 222 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Homeobox C5

Target: Homeobox C5 (HOXC5)

Alternative Name: HOXC5 (HOXC5 Products)

Synonyms: ZF-25 antibody, hox-3.4 antibody, hoxc5 antibody, z-142 antibody, XlHbox5 antibody, hoxc5-A antibody, CP11 antibody, HOX3 antibody, HOX3D antibody, AI181837 antibody, Hox-3.4 antibody, Hox-6.2 antibody, homeobox C5 antibody, homeo box C5 antibody, homeobox C5a antibody, homeobox C5 L homeolog antibody, translation initiation factor IF-2 antibody, HOXC5 antibody, Hoxc5 antibody, hoxc5a antibody, hoxc5.L antibody, LOC607625 antibody

Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only.
Alias Symbols: CP11, HOX3, HOX3D
Protein Interaction Partner: UBC,
Protein Size: 222

Molecular Weight: 25 kDa

Gene ID: 3222

NCBI Accession: NM_018953, NP_061826

UniProt: Q00444