anti-TCF7 antibody (Transcription Factor 7 (T-Cell Specific, HMG-Box)) (Middle Region)

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Antigen
Synonyms TCF-1, AI465550, Tcf1
Alternatives
Epitope
Middle Region
(31), (10), (7), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(92), (22), (9), (5), (5), (1), (1), (1)
Host
Rabbit
(71), (11), (10)
Clonality
Polyclonal
Conjugate
This TCF7 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application
Western Blotting (WB)
(77), (50), (9), (6), (6), (5), (3), (2), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human TCF7
Blocking Peptide Blocking peptide for this product available: Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (Middle Region) peptide (ABIN984903)
Sequence MQLYPGWSAR DNYGKKKRRS REKHQESTTE TNWPRELKDG NGQESLSMSS
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against TCF7. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TCF7 (TCF7 Antibody Abstract)
Background The T-cell-specific transcription factor TCF7 activates genes involved in immune regulation and is a candidate locus for genetic susceptibility to type 1 diabetes.
Molecular Weight 30 kDa
Gene ID 6932
NCBI Accession NM_201633, NP_963964
Research Area Stem Cells, Wnt, Transcription Factors
Pathways WNT Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 269 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-TCF7 antibody (Transcription Factor 7 (T-Cell Specific, HMG-Box)) (Middle Region) (ABIN486835) WB Suggested Anti-TCF7 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Western Blotting (WB) image for anti-TCF7 antibody (Transcription Factor 7 (T-Cell Specific, HMG-Box)) (Middle Region) (ABIN486835) Host: Rabbit
Target Name: TCF7
Sample Tissue: Human Fetal Brain
...
Western Blotting (WB) image for anti-TCF7 antibody (Transcription Factor 7 (T-Cell Specific, HMG-Box)) (Middle Region) (ABIN486835) Host: Rabbit
Target Name: TCF7
Sample Tissue: Human Fetal Lung
A...
Background publications Willinger, Freeman, Herbert et al.: "Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 3, pp. 1439-46, 2006 (PubMed).

Catalog No. ABIN486835
$289.00
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