GTF3C2 antibody (Middle Region)

Catalog No. ABIN486879

Product Details anti-GTF3C2 Antibody

Target: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Horse, Rat, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF3C2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YKADLIPYQD SPEGPDHSSA SSGVPNPPKA RTYTETVNHH YLLFQDTDLG

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against GTF3C2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTF3C2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 911 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF3C2

Target: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Alternative Name: GTF3C2 (GTF3C2 Products)

Synonyms: TFIIIC110 antibody, GTF3C2 antibody, MGC155253 antibody, TF3C-beta antibody, DKFZp469M0113 antibody, 1300004C11Rik antibody, 2610510G03Rik antibody, AI225816 antibody, AU041069 antibody, mKIAA0011 antibody, TFIIIC-BETA antibody, general transcription factor IIIC subunit 2 antibody, general transcription factor IIIC, polypeptide 2, beta antibody, Gtf3c2 antibody, GTF3C2 antibody

Background: GTF3C2 is required for RNA polymerase III-mediated transcription. GTF3C2 is a component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. GTF3C2 may play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.
Alias Symbols: KIAA0011, TFIIIC-BETA, TFIIIC110
Protein Interaction Partner: UBC, PASK, RPA3, RPA2, RPA1, GRIA2, GTF3C6, GTF3C3, GTF3C4, GTF3C5, GTF3C1, HHV8GK18_gp81, SUMO2, SMARCAD1, MYC, EP300, GTF3A, RB1, POLR3C, TBP,
Protein Size: 911

Molecular Weight: 101 kDa

Gene ID: 2976

NCBI Accession: NM_001521, NP_001512

UniProt: Q8WUA4