JAZF1 antibody (N-Term)

Catalog No. ABIN487148

Product Details anti-JAZF1 Antibody

Target: JAZF1 (JAZF Zinc Finger 1 (JAZF1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAZF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IDTDPRVLEK QELQQPTYVA LSYINRFMTD AARREQESLK KKIQPKLSLT

Predicted Reactivity: Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against JAZF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human JAZF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 243 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for JAZF1

Target: JAZF1 (JAZF Zinc Finger 1 (JAZF1))

Alternative Name: JAZF1 (JAZF1 Products)

Synonyms: TIP27 antibody, ZNF802 antibody, JAZF1 antibody, AI591476 antibody, C820002C15 antibody, Jaz1 antibody, Tip27 antibody, zgc:103778 antibody, JAZF zinc finger 1 antibody, JAZF zinc finger 1b antibody, JAZF1 antibody, Jazf1 antibody, jazf1b antibody

Background: JAZF1 is a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: DKFZp761K2222, TIP27, ZNF802
Protein Interaction Partner: NR2C2, RXRA, PPARG, UBC,
Protein Size: 243

Molecular Weight: 27 kDa

Gene ID: 221895

NCBI Accession: NM_175061, NP_778231

UniProt: Q86VZ6