KRT8 antibody (Middle Region)

Catalog No. ABIN487178

Product Details anti-KRT8 Antibody

Target: KRT8 (Keratin 8 (KRT8))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Pig, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: QSLAGKHGDD LRRTKTEISE MNRNISRLQA EIEGLKGQRA SLEAAIADAE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against KRT8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KRT8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT8

Target: KRT8 (Keratin 8 (KRT8))

Alternative Name: KRT8 (KRT8 Products)

Synonyms: CARD2 antibody, CK-8 antibody, CK8 antibody, CYK8 antibody, K2C8 antibody, K8 antibody, KO antibody, AA960620 antibody, AL022697 antibody, AU019895 antibody, Card2 antibody, EndoA antibody, Krt-2.8 antibody, Krt2-8 antibody, CYKER antibody, KRT2-8 antibody, KERATIN8 antibody, ck8 antibody, cyk8 antibody, k2c8 antibody, card2 antibody, krt2-5 antibody, MGC69490 antibody, KRT8 antibody, DreK8 antibody, cb186 antibody, krt2-8 antibody, sb:cb186 antibody, wu:fa20h05 antibody, wu:fa95h10 antibody, wu:fb96c06 antibody, zf-K8 antibody, zfk8 antibody, DKFZp468F2127 antibody, keratin 8 antibody, keratin 8 S homeolog antibody, KRT8 antibody, Krt8 antibody, krt8.S antibody, krt8 antibody

Background: KRT8 together with KRT19, help to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Alias Symbols: CARD2, CK8, CYK8, K2C8, K8, KO, CK-8
Protein Interaction Partner: KRT31, KRT15, KRT13, KRT40, TFIP11, KRT38, UBC, MDM2, ASB12, EED, GRB2, FBXO25, PAN2, IQCB1, IKBKG, VCAM1, NOS2, KRT18, KPNA2, ITGA4, FN1, ATF2, CDH1, STAM2, CRK, UBASH3B, APEX1, RCHY1, SQSTM1, SUMO1, SUMO2, SUMO3, MAPK8, QRSL1, YWHAQ, TJP1, TADA2A, USP32
Protein Size: 483

Molecular Weight: 54 kDa

Gene ID: 3856

NCBI Accession: NM_002273, NP_002264

UniProt: P05787