RHOD (C-Term) antibody

Details for Product No. ABIN487183
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Antigen
Synonyms ARHD, RHOHP1, RHOM, Rho, AI326383, Arhd, RhoHP1, RhoM
Epitope
C-Term
(9), (3), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Human
(20)
Host
Rabbit
(17), (3)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(19), (12), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN487183
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human RHOD
Sequence NGLEPVTYHR GQEMARSVGA VAYLECSARL HDNVHAVFQE AAEVALSSRG
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against RHOD. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Background Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. RHOD binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton.
Molecular Weight 23 kDa
Gene ID 29984
NCBI Accession NM_014578, NP_055393
UniProt O00212
Research Area Signaling, Cytoskeleton, Microfilaments, Organelles
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 210 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-RHOD (C-Term) antibody Immunohistochemistry with Tonsil tissue at an antibody concentration of 5µg/ml using anti-RHOD antibody (ARP42414_P050)
Background publications Tong, Chugha, Hota et al.: "Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain." in: The Journal of biological chemistry, Vol. 282, Issue 51, pp. 37215-24, 2007 (PubMed).

Validation Images
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