PAPD4 antibody (N-Term)

Catalog No. ABIN487221

Product Details anti-PAPD4 Antibody

Target: PAPD4 (PAP Associated Domain Containing 4 (PAPD4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPD4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRKRLSDEKN LPLDGKRQRF HSPHQEPTVV NQIVPLSGER RYSMPPLFHT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PAPD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAPD4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 484 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PAPD4 antibody (ABIN487221)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for PAPD4

Target: PAPD4 (PAP Associated Domain Containing 4 (PAPD4))

Alternative Name: PAPD4 (PAPD4 Products)

Synonyms: GLD2 antibody, 8030446C20Rik antibody, AI649009 antibody, GLD-2 antibody, Gld2 antibody, zgc:110560 antibody, poly(A) RNA polymerase D4, non-canonical antibody, PAP associated domain containing 4 antibody, Poly(A) RNA polymerase gld-2 antibody, PAPD4 antibody, Papd4 antibody, papd4 antibody, gld-2 antibody

Background: PAPD4 is a cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. PAPD4 belongs to the DNA polymerase type-B-like family, GLD2 subfamily.
Alias Symbols: FLJ38499, GLD2
Protein Interaction Partner: RBPMS, CALCOCO2, SOX2, ELAVL1,
Protein Size: 484

Molecular Weight: 56 kDa

Gene ID: 167153

NCBI Accession: NM_173797, NP_776158

UniProt: Q6PIY7