Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibody

Details for Product No. ABIN487290
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Antigen
Synonyms
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15, Crk4, Cdkn7, AI323415, AI528512, C230069N13, zgc:85821, C-MOS, CD 7, CDK7, CG3319, DmCDK7, DmCdk7, DmMO15, DmMo15, Dmcdk7, Dmel\\CG3319, Mo15, cdk-7, cdk7, dCdk ... show more
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15, Crk4, Cdkn7, AI323415, AI528512, C230069N13, zgc:85821, C-MOS, CD 7, CDK7, CG3319, DmCDK7, DmCdk7, DmMO15, DmMo15, Dmcdk7, Dmel\\CG3319, Mo15, cdk-7, cdk7, dCdk7, p40[MO15], p40MO15, stk1, cak1, cdkn7, p39mo15 show less
Epitope
C-Term
(25), (18), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(136), (55), (36), (16), (15), (15), (5), (2), (1)
Host
Rabbit
(89), (54)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(105), (49), (41), (29), (28), (20), (19), (18), (17), (10), (5), (4), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN487290
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
Options
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the C terminal of human CDK7
Sequence NRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALE QGGLPKKLIF
Predicted Reactivity Bovine : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Dog : 90 %, Guinea pig : 90 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name CDK7
Background Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti
Molecular Weight 39 kDa
Gene ID 1022
NCBI Accession NM_001799, NP_001790
UniProt P50613
Research Area Cell Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 346 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibody WB Suggested Anti-CDK7 Antibody Titration: 1ug/ml
Positive Control: Jurkat cell lysate
Background publications Tassan, Schultz, Bartek et al.: "Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)." in: The Journal of cell biology, Vol. 127, Issue 2, pp. 467-78, 1994 (PubMed).

Hosts (89), (54)
Reactivities (136), (55), (36), (16), (15), (15), (5), (2), (1)
Applications (105), (49), (41), (29), (28), (20), (19), (18), (17), (10), (5), (4), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Epitopes (25), (18), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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