Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibody

Details for Product No. ABIN487290
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Antigen
Synonyms
CD 7, CDK7, CG3319, DmCDK7, DmCdk7, DmMO15, DmMo15, Dmcdk7, Dmel\\CG3319, Mo15, cdk-7, cdk7, dCdk7, p40[MO15], MO15, cak1, stk1, cdkn7, p39mo15, p40MO15, CAK1, CDKN7, HCAK, STK1, p39MO15, AI323415, AI ... show more
CD 7, CDK7, CG3319, DmCDK7, DmCdk7, DmMO15, DmMo15, Dmcdk7, Dmel\\CG3319, Mo15, cdk-7, cdk7, dCdk7, p40[MO15], MO15, cak1, stk1, cdkn7, p39mo15, p40MO15, CAK1, CDKN7, HCAK, STK1, p39MO15, AI323415, AI528512, C230069N13, Cdkn7, Crk4, zgc:85821, C-MOS show less
Epitope
C-Term
(34), (29), (13), (7), (6), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(158), (59), (34), (16), (16), (15), (7), (1), (1)
Host
Rabbit
(119), (48)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(128), (66), (50), (32), (29), (20), (20), (15), (15), (11), (8), (4), (3), (2), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN487290
229.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human CDK7
Sequence NRPGPTPGCQ LPRPNCPVET LKEQSNPALA IKRKRTEALE QGGLPKKLIF
Predicted Reactivity Bovine : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Dog : 90 %, Guinea pig : 90 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name CDK7
Background Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti
Molecular Weight 39 kDa
Gene ID 1022
NCBI Accession NP_001790, NM_001799
UniProt P50613
Research Area Cell Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 346 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibody WB Suggested Anti-CDK7 Antibody Titration: 1ug/ml
Positive Control: Jurkat cell lysate
Background publications Tassan, Schultz, Bartek et al.: "Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)." in: The Journal of cell biology, Vol. 127, Issue 2, pp. 467-78, 1994 (PubMed).

Validation Images
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