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Antibodies
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anti-Lymphotoxin alpha (TNF Superfamily, Member 1) (LTA) antibody
Lymphotoxin alpha (TNF Superfamily, Member 1) (LTA) antibody
| Antigen |
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| Synonyms |
LT, TNFB, TNFSF1, Ltx, Tnfb, LT[a], LT-[a], hlb382, LTalpha, Tnfsf1b, LT-alpha, TNF-beta, MGC117668, LT-a, tnfb, tnfsf1, LTA |
| Clonality |
Monoclonal (AT15A3) |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
Immunofluorescence (IF) (21), Western Blotting (WB) (21), Flow Cytometry (FACS) (20), Enzyme Immunoassay (EIA) (9), ELISA (6), Blocking Antibody (Inhibition) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Functional Studies (Func) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Neutralization (Neut) (1)
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| Catalog no. |
ABIN487355 |
| Quantity |
50 µl (1.0 mg/ml) (Variants) |
| Price |
265.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: TNFB, TNFSF1, LTA, LT-alpha, Tumor necrosis factor ligand superfamily member 1
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Alternative name
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TNF-beta / Lymphotoxin-alpha
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Gene ID
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4049
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Swiss-Prot
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P01374
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Immunogen
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Recombinant human LTA (35-205aa) purified from E. coli
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Cross-Reactivity
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Human, Mouse (Murine)
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Isotype
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IgG2b (Matching secondary antibodies)
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Clone
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AT15A3
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Description
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Lymphotoxin-alpha (LT-alpha, LTA) is member of the TNF ligand superfamily, bind the sameTNF receptor and mediate similar pleiotropic effect. LTA, located within the MHC III regionof chromosome 6, show close linkage to the HLA class I (HLA-B) and class II (HLA-DR)genes. LTA is proinflammatory cytokine with important biological activity andimmunomodulatory function and be known to influence a variety of cellular response. Inparticular, Polymorphism in the gene encoding LTA appears to contribute to infectiousdisease susceptibility and infection.
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Specificity
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The antibody recognizes human and mouse LTA. Other species not tested.
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Application Notes
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ELISA. Western blot (1: 250 - 1: 1000). Immunofluorescence (1: 250 - 1: 500). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Purification
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Purified
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Buffer
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PBS, pH 7.4, containing 0.09% sodium azide
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Storage
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Store the antibody undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°Cfor longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Cytokines, Growth Factors, Receptors, Immunology, Inflammation
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Restrictions
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For Research Use only
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Alternatives for antigen "Lymphotoxin alpha (TNF Superfamily, Member 1) (LTA)", type "Antibodies"
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Hosts
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Rabbit (36), Mouse (4), Sheep (1)
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Reactivities
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Human (39), Mouse (Murine) (20), Rat (Rattus) (20), Cow (Bovine) (15), Dog (Canine) (15), Horse (Equine) (15), Rabbit (15)
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Applications
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Immunofluorescence (IF) (21), Western Blotting (WB) (21), Flow Cytometry (FACS) (20), Enzyme Immunoassay (EIA) (9), ELISA (6), Blocking Antibody (Inhibition) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Functional Studies (Func) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Neutralization (Neut) (1)
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Conjugates
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Biotin (3), FITC (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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Center (1)
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