P105 (NFKB) antibody
| Antigen |
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| Clonality |
Monoclonal (2B3) |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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| Catalog no. |
ABIN487358 |
| Quantity |
0.5 ml |
| Price |
350.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: PANA, Proliferation Associated Nuclear Antigen, Proliferation Marker
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Alternative name
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P105
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Immunogen
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Activated peripheral blood nuclei
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Cross-Reactivity
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Human
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Isotype
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IgM (Matching secondary antibodies)
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Clone
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2B3
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Description
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The p105 protein found in all human cells in a dimeric form (105 kD) and monomeric form(41 kD), is a proliferation-associated nuclear antigen that is absent in non-cycling cells inthe Go phase. This protein is important in the synthesis and transport of RNA in the cellregulation cycle. During G2 , and mitosis, this protein is increased possibly due to theunmasking of nucleolar antigens.
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Specificity
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The antibody recognizes human p105 protein. Other species not tested. Cellular localization: Nuclear.
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Application Notes
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Western Blot (1: 100 - 1: 200). Immunohistochemistry on frozen and Paraffin sections (1: 50 - 1: 100). Please note: Formalin-fixed paraffin-embedded (FFPE) tissue sections require pepsin ortrypsin digestion. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Supernatant
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Buffer
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PBS, pH 7.2, containing 0.02% BSA and 0.09% sodium azide
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Storage
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Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. Shelf life: one year from despatch.
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Research Area
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Transcription Factors
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Restrictions
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For Research Use only
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Alternatives for antigen "P105 (NFKB)", type "Antibodies"
