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EYA1 antibody (Internal Region)

EYA1 Reactivity: Human, Mouse, Rat, Cow, Dog WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN487975
  • Target See all EYA1 Antibodies
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    Binding Specificity
    • 15
    • 15
    • 10
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 35
    • 24
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Dog
    Host
    • 45
    • 1
    • 1
    Goat
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EYA1 antibody is un-conjugated
    Application
    • 27
    • 23
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to EYA1.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-TDPTAEYSTIHSP, from the internal region of the protein sequence according to NP_742057.1, NP_000494.2, NP_742056.1.
    Top Product
    Discover our top product EYA1 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/16000. Western blot: Approx 55 kDa band observed in lysates of cell lline HEK293 (calculated MWof 60.5 kDa according to NP_742056.1). Recommended concentration: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    EYA1 (Eyes Absent Homolog 1 (EYA1))
    Alternative Name
    EYA1 (EYA1 Products)
    Synonyms
    EYA1 antibody, bop antibody, bor antibody, XEya1 antibody, wu:fc13c10 antibody, zgc:100770 antibody, BOP antibody, BOR antibody, BOS1 antibody, EYA transcriptional coactivator and phosphatase 1 antibody, EYA transcriptional coactivator and phosphatase 1 L homeolog antibody, EYA1 antibody, eya1 antibody, Eya1 antibody, eya1.L antibody
    Background
    EYA1 (Eyes Absent Homolog 1) is a member of the eyes absent (EYA) family of proteins. EYA1 plays a role in transcriptional regulation during organogenesis. It is thought play a role in the development of the kidney, branchial arches, eye and ear. EYA1 is thought to coactivate SIX2, SIX4 and SIX5. EYA1 has intrinsic protein phosphatase activity, and dephosphorylates proteins such as Histone H2.AX phosphorylated on Y142. It is thought to play a role in promoting efficient DNA repair over apoptosis in response to genotypic stress.Synonyms: Eyes absent homolog 1
    Gene ID
    2138
    NCBI Accession
    NP_000494
    UniProt
    Q99502
    Pathways
    Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus
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