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MXD3 antibody (C-Term)

MXD3 Reactivity: Human IF, EIA, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN487991
  • Target See all MXD3 Antibodies
    MXD3 (MAX Dimerization Protein 3 (MXD3))
    Binding Specificity
    • 11
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 38
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    • 3
    • 1
    Goat
    Clonality
    • 35
    • 4
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MXD3 antibody is un-conjugated
    Application
    • 25
    • 19
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Sequence
    c-QEHSYSHGGG AWL
    Specificity
    This antibody is expected to recognise isoform a (NP_112590.1) only.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    Synthetic peptide from the C-Terminus of Human MAD3 (NP_112590.1)
  • Application Notes
    Peptide ELISA: 1/4000. Immunofluorescence: This product has been successfully used by an anonymous customeron methanol-fixed and 0.5 % TX100-permeabilized HeLa cells, staning thecytoplasm.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    MXD3 (MAX Dimerization Protein 3 (MXD3))
    Alternative Name
    MAD3 (MXD3 Products)
    Synonyms
    Mad3 antibody, BHLHC13 antibody, MAD3 antibody, MYX antibody, 4631412E13Rik antibody, bHLHc13 antibody, Mad antibody, zgc:66281 antibody, Myx antibody, MAX dimerization protein 3 antibody, Max dimerization protein 3 antibody, MAX dimerization protein 3 L homeolog antibody, mxd3 antibody, MXD3 antibody, Mxd3 antibody, mxd3.L antibody
    Background
    MAD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.Synonyms: MAD-3, MXD3, Max-interacting transcriptional repressor MAD3
    Gene ID
    83463
    NCBI Accession
    NP_001136407
    UniProt
    Q9BW11
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