Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.2 containing 50 % Glycerol without preservatives.
Preservative
Without preservative
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
Cdk6 (Cyclin-dependent kinase-6) is a 38-40 kDa member of the Cdk family of mitotic kinases involved in cell cycle progression. The Cdk6 phosphoprotein, like Cdk4, associates with D-cyclins to regulate cell proliferation. Following translocation to the nucleus, the Cdk6 is phosphorylated by CAK, and the Cdk6 complex, in association with PCNA, phosphorylates the retinoblastoma (Rb) protein. Overexpression of Cdk6 has been associated with several different types of cancer.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE